1	["benign","0.000114142",4,"Low","Uncertain","OFD1-Q545R",true,"benign","Homozygous",-1]
2	["benign","0.000185908",2,"Low","Likely","HNF4A-V169I",true,"benign","Heterozygous",-1]
3	["benign","0.000185908",4,"Low","Uncertain","JAG1-N1110T",true,"benign","Heterozygous",-1]
4	["benign","0.000185908",4,"Low","Uncertain","NOTCH2-P227H",true,"benign","Heterozygous",-1]
5	["benign","0.000278862",4,"Low","Likely","ERCC2-L461V",true,"benign","Heterozygous",-1]
6	["benign","0.000278914",3,"Low","Uncertain","OPTN-R545Q",true,"benign","Heterozygous",1]
7	["benign","0.000465809",4,"Low","Uncertain","WDR36-H212P",true,"benign","Heterozygous",-1]
8	["benign","0.000470189",5,"Low","Uncertain","NKX2-5-E21Q",true,"benign","Heterozygous",-1]
9	["benign","0.000557724",4,"Low","Uncertain","HPS1-R263W",true,"benign","Heterozygous",-1]
10	["benign","0.000576147",4,"Low","Uncertain","SEPT9-R355W",true,"benign","Heterozygous",-1]
11	["benign","0.000650678",4,"Low","Uncertain","FLNB-G925C",true,"benign","Heterozygous",-1]
12	["benign","0.000650678",5,"Low","Likely","OCA2-H615R",true,"benign","Heterozygous",0]
13	["benign","0.000650678",5,"Low","Likely","OCA2-H615R",true,"benign","Homozygous",0]
14	["benign","0.000743632",4,"Low","Uncertain","NDRG1-H41R",true,"benign","Heterozygous",-1]
15	["benign","0.00092954",5,"Low","Uncertain","MSH6-V509A",true,"benign","Heterozygous",-1]
16	["benign","0.00102612",4,"Low","Uncertain","DOK7-P214L",true,"benign","Heterozygous",-1]
17	["benign","0.00124507",5,"Low","Likely","SCN9A-K655R",true,"benign","Heterozygous",-1]
18	["benign","0.0013016",4,"Low","Uncertain","RYR1-G893S",true,"benign","Heterozygous",-1]
19	["benign","0.00139431",4,"Low","Uncertain","DCTN1-R1049Q",true,"benign","Heterozygous",-1]
20	["benign","0.00148726",5,"Low","Uncertain","MYH9-R1400W",true,"benign","Heterozygous",-1]
21	["benign","0.00148726",6,"Low","Uncertain","CAV3-C72W",true,"benign","Heterozygous",-1]
22	["benign","0.00158022",5,"Low","Likely","PARK2-A82E",true,"benign","Heterozygous",-1]
23	["benign","0.00170487",6,"Low","Likely","MYO7A-R302H",true,"benign","Heterozygous",-1]
24	["benign","0.00176613",4,"Low","Uncertain","COL6A3-D491H",true,"benign","Heterozygous",-1]
25	["benign","0.00185908",6,"Low","Likely","MEFV-K695R",true,"benign","Heterozygous",-1]
26	["benign","0.00204499",4,"Low","Uncertain","COL6A3-T492S",true,"benign","Heterozygous",-1]
27	["benign","0.00223131",3,"Low","Uncertain","PKHD1-G2285E",true,"benign","Heterozygous",-1]
28	["benign","0.00269567",4,"Low","Uncertain","BRCA1-R841W",true,"benign","Heterozygous",-1]
29	["benign","0.00269567",5,"Low","Uncertain","GJB2-V27I",true,"benign","Heterozygous",-1]
30	["benign","0.00269567",5,"Low","Uncertain","GJB2-V27I",true,"benign","Homozygous",-1]
31	["benign","0.00288158",5,"Low","Uncertain","MLC1-N218K",true,"benign","Heterozygous",-1]
32	["benign","0.00288158",6,"Low","Likely","HEXA-R247W",true,"benign","Carrier (Heterozygous)",-1]
33	["benign","0.00316279",4,"Low","Uncertain","LPIN2-L504F",true,"benign","Heterozygous",-1]
34	["benign","0.00326539",6,"Low","Likely","CYP1B1-Y81N",true,"benign","Carrier (Heterozygous)",-1]
35	["benign","0.00362521",4,"Low","Uncertain","DNAH5-E1756K",true,"benign","Heterozygous",-1]
36	["benign","0.00362521",5,"Low","Uncertain","HTRA2-G399S",true,"benign","Heterozygous",-1]
37	["benign","0.00390407",2,"Low","Likely","ZEB1-Q840P",true,"benign","Heterozygous",-1]
38	["benign","0.00408998",5,"Low","Likely","ABCA4-L1970F",true,"benign","Carrier (Heterozygous)",-1]
39	["benign","0.00427589",5,"Low","Uncertain","BRCA1-R1347G",true,"benign","Heterozygous",-1]
40	["benign","0.00436884",4,"Low","Likely","MYO1A-R93X",true,"benign","Heterozygous",-1]
41	["benign","0.00466531",4,"Low","Uncertain","XPC-L16V",true,"benign","Heterozygous",-1]
42	["benign","0.00466531",4,"Low","Uncertain","XPC-L16V",true,"benign","Homozygous",-1]
43	["benign","0.00474066",4,"Low","Uncertain","USH2A-G4692R",true,"benign","Heterozygous",-1]
44	["benign","0.00474507",3,"Low","Likely","CHST8-R77W",true,"benign","Carrier (Heterozygous)",-1]
45	["benign","0.00485625",4,"Low","Likely","PKP2-D26N",true,"benign","Heterozygous",-1]
46	["benign","0.00492748",5,"Low","Likely","ITGB2-R586W",true,"benign","Heterozygous",-1]
47	["benign","0.00542169",4,"Low","Uncertain","ABCB11-R698H",true,"benign","Heterozygous",-1]
48	["benign","0.00557724",3,"Low","Likely","EPOR-N487S",true,"benign","Heterozygous",-1]
49	["benign","0.00576315",4,"Low","Likely","MSH6-V878A",true,"benign","Heterozygous",-1]
50	["benign","0.00585611",3,"Low","Uncertain","TYK2-A928V",true,"benign","Heterozygous",-1]
51	["benign","0.00622792",3,"Low","Likely","MYO1A-V306M",true,"benign","Heterozygous",-1]
52	["benign","0.00641383",4,"Low","Uncertain","ATM-V2079I",true,"benign","Heterozygous",-1]
53	["benign","0.00644137",4,"Low","Uncertain","VCAN-T689A",true,"benign","Heterozygous",-1]
54	["benign","0.00650678",4,"Low","Uncertain","COG1-T350M",true,"benign","Heterozygous",-1]
55	["benign","0.00650678",4,"Low","Uncertain","COG1-T350M",true,"benign","Homozygous",-1]
56	["benign","0.00650678",4,"Low","Uncertain","FLG-H2463D",true,"benign","Heterozygous",-1]
57	["benign","0.00659974",6,"Low","Uncertain","SDHD-H50R",true,"benign","Heterozygous",-1]
58	["benign","0.00725177",4,"Low","Uncertain","PPOX-P256R",true,"benign","Carrier (Heterozygous)",-1]
59	["benign","0.00771519",5,"Low","Well-established","PTCH1-T728M",true,"benign","Heterozygous",-1]
60	["benign","0.00780814",4,"Low","Uncertain","NOTCH3-V1952M",true,"benign","Heterozygous",-1]
61	["benign","0.0078125",2,"Low","Uncertain","PMS1-Y90Shift",true,"benign","Heterozygous",-1]
62	["benign","0.0078125",4,"Low","Uncertain","ALK-L1033P",true,"benign","Heterozygous",-1]
63	["benign","0.0078125",4,"Low","Uncertain","LYST-R159K",true,"benign","Heterozygous",-1]
64	["benign","0.0078125",4,"Low","Uncertain","NDRG1-R325W",true,"benign","Heterozygous",-1]
65	["benign","0.0078125",4,"Low","Uncertain","NF1-Q2721R",true,"benign","Heterozygous",-1]
66	["benign","0.0078125",4,"Low","Uncertain","SIL1-V332M",true,"benign","Heterozygous",-1]
67	["benign","0.0078125",4,"Low","Uncertain","SYNE1-V5606L",true,"benign","Heterozygous",-1]
68	["benign","0.00799405",5,"Low","Uncertain","POLG-Y831C",true,"benign","Heterozygous",-1]
69	["benign","0.008087",5,"Low","Likely","SDHD-G12S",true,"benign","Heterozygous",-1]
70	["benign","0.00817996",3,"Low","Uncertain","MLH3-E624Q",true,"benign","Heterozygous",-1]
71	["benign","0.00818148",4,"Low","Uncertain","ATM-S707P",true,"benign","Heterozygous",-1]
72	["benign","0.00846827",3,"Low","Likely","ABCC9-V734I",true,"benign","Heterozygous",-1]
73	["benign","0.00847458",4,"Low","Uncertain","DNAH5-E758G",true,"benign","Heterozygous",-1]
74	["benign","0.00878754",5,"Low","Likely","CEP290-D664G",true,"benign","Heterozygous",-1]
75	["benign","0.00901654",4,"Low","Uncertain","FKTN-N446D",true,"benign","Heterozygous",-1]
76	["benign","0.00929541",4,"Low","Uncertain","DSP-E1833V",true,"benign","Heterozygous",-1]
77	["benign","0.0100948",4,"Low","Uncertain","COL4A4-G999E",true,"benign","Heterozygous",1]
78	["benign","0.0104109",5,"Low","Uncertain","DSP-R1537C",true,"benign","Heterozygous",-1]
79	["benign","0.0104109",5,"Low","Uncertain","DSP-R1537C",true,"benign","Homozygous",-1]
80	["benign","0.0104109",5,"Low","Uncertain","SDHB-S163P",true,"benign","Heterozygous",-1]
81	["benign","0.0105968",5,"Low","Uncertain","EDAR-V370A",true,"benign","Heterozygous",-1]
82	["benign","0.0105968",5,"Low","Uncertain","EDAR-V370A",true,"benign","Homozygous",-1]
83	["benign","0.0107827",2,"Low","Uncertain","AARS-K967M",true,"benign","Heterozygous",-1]
84	["benign","0.0107827",2,"Low","Uncertain","AARS-K967M",true,"benign","Homozygous",-1]
85	["benign","0.0108696",3,"Low","Uncertain","BMP15-A180T",true,"benign","Heterozygous",-1]
86	["benign","0.0110615",4,"Low","Likely","MSH2-G322D",true,"benign","Heterozygous",-1]
87	["benign","0.0111545",4,"Low","Uncertain","RPGRIP1L-A1183G",true,"benign","Heterozygous",-1]
88	["benign","0.0112474",3,"Low","Uncertain","RELN-G1280E",true,"benign","Heterozygous",-1]
89	["benign","0.0113425",5,"Low","Likely","TGM1-V518M",true,"benign","Heterozygous",-1]
90	["benign","0.0119025",4,"Low","Uncertain","POLG2-G416A",true,"benign","Heterozygous",-1]
91	["benign","0.0119025",4,"Low","Uncertain","POLG2-G416A",true,"benign","Homozygous",-1]
92	["benign","0.0128277",4,"Low","Likely","PKHD1-V3960I",true,"benign","Heterozygous",-1]
93	["benign","0.0128277",4,"Low","Likely","PKHD1-V3960I",true,"benign","Homozygous",-1]
94	["benign","0.0130136",5,"Low","Uncertain","CAPN3-T184M",true,"benign","Heterozygous",-1]
95	["benign","0.0131995",4,"Low","Uncertain","NOTCH3-H1133Q",true,"benign","Heterozygous",-1]
96	["benign","0.0135738",3,"Low","Uncertain","LRRK2-N2081D",true,"benign","Heterozygous",-1]
97	["benign","0.015625",4,"Low","Uncertain","CFTR-I556V",true,"benign","Carrier (Heterozygous)",-1]
98	["benign","0.015625",4,"Low","Uncertain","NOTCH3-P496L",true,"benign","Heterozygous",-1]
99	["benign","0.015625",4,"Low","Uncertain","NOTCH3-P496L",true,"benign","Homozygous",-1]
100	["benign","0.0157092",3,"Low","Uncertain","USH2A-V230M",true,"benign","Carrier (Heterozygous)",-1]
101	["benign","0.0157473",5,"Low","Uncertain","UNC13D-R928C",true,"benign","Heterozygous",-1]
102	["benign","0.0161654",4,"Low","Uncertain","OTOF-R773C",true,"benign","Heterozygous",-1]
103	["benign","0.0161891",3,"Low","Likely","GABRD-R220H",true,"benign","Heterozygous",-1]
104	["benign","0.0166388",5,"Low","Uncertain","USH1C-V130I",true,"benign","Heterozygous",-1]
105	["benign","0.0167317",3,"Low","Uncertain","ALOX12B-P127S",true,"benign","Heterozygous",0]
106	["benign","0.016814",5,"Low","Likely","HTRA2-A141S",true,"benign","Heterozygous",-1]
107	["benign","0.0171965",4,"Low","Uncertain","UNC13D-A59T",true,"benign","Heterozygous",-1]
108	["benign","0.0171965",4,"Low","Uncertain","UNC13D-A59T",true,"benign","Homozygous",-1]
109	["benign","0.0172895",6,"Low","Uncertain","FAH-R341W",true,"benign","Carrier (Heterozygous)",-1]
110	["benign","0.0177542",5,"Low","Uncertain","CYP27A1-P384L",true,"benign","Heterozygous",-1]
111	["benign","0.0179176",4,"Low","Likely","RYR2-G1885E",true,"benign","Carrier (Heterozygous)",-1]
112	["benign","0.0179176",4,"Low","Likely","RYR2-G1885E",true,"benign","Homozygous",1]
113	["benign","0.0180678",4,"Low","Uncertain","OTOF-R822W",true,"benign","Heterozygous",-1]
114	["benign","0.0200037",4,"Low","Uncertain","TERT-A279T",true,"benign","Heterozygous",-1]
115	["benign","0.0200781",4,"Low","Uncertain","NEUROD1-P197H",true,"benign","Heterozygous",-1]
116	["benign","0.0206645",5,"Low","Uncertain","DMD-H2921R",true,"benign","Heterozygous",-1]
117	["benign","0.0206645",5,"Low","Uncertain","DMD-H2921R",true,"benign","Homozygous",-1]
118	["benign","0.0216583",4,"Low","Likely","FANCA-M717I",true,"benign","Heterozygous",-1]
119	["benign","0.022309",4,"Low","Uncertain","GJB3-R32W",true,"benign","Heterozygous",-1]
120	["benign","0.023413",4,"Low","Uncertain","MUSK-T100M",true,"benign","Heterozygous",-1]
121	["benign","0.0234375",4,"Low","Uncertain","RNASEH2B-I309Shift",true,"benign","Heterozygous",-1]
122	["benign","0.0234375",4,"Low","Uncertain","RNASEH2B-I309Shift",true,"benign","Homozygous",-1]
123	["benign","0.0237033",5,"Low","Uncertain","GAA-D91N",true,"benign","Carrier (Heterozygous)",-1]
124	["benign","0.0237033",5,"Low","Uncertain","GAA-D91N",true,"benign","Homozygous",1]
125	["benign","0.0244469",5,"Low","Uncertain","PALB2-E672Q",true,"benign","Heterozygous",-1]
126	["benign","0.0252835",4,"Low","Likely","COL9A2-T246M",true,"benign","Heterozygous",-1]
127	["benign","0.0254001",4,"Low","Uncertain","NSD1-A2546T",true,"benign","Heterozygous",-1]
128	["benign","0.0258412",3,"Low","Uncertain","ENPP1-R774C",true,"benign","Heterozygous",-1]
129	["benign","0.0269529",4,"Low","Likely","DMD-R2155W",true,"benign","Heterozygous",-1]
130	["benign","0.0269529",4,"Low","Likely","DMD-R2155W",true,"benign","Homozygous",-1]
131	["benign","0.0290946",4,"Low","Likely","SLC45A2-E272K",true,"benign","Heterozygous",-1]
132	["benign","0.0290946",4,"Low","Likely","SLC45A2-E272K",true,"benign","Homozygous",-1]
133	["benign","0.0295359",5,"Low","Likely","ADA-D8N",true,"benign","Heterozygous",1]
134	["benign","0.0295359",5,"Low","Likely","ADA-D8N",true,"benign","Homozygous",1]
135	["benign","0.0301845",5,"Low","Uncertain","GAA-E689K",true,"benign","Heterozygous",0]
136	["benign","0.0301845",5,"Low","Uncertain","GAA-E689K",true,"benign","Homozygous",0]
137	["benign","0.0310451",3,"Low","Uncertain","CASP8-M1T",true,"benign","Heterozygous",-1]
138	["benign","0.0316044",5,"Low","Uncertain","ABCA4-R943Q",true,"benign","Heterozygous",-1]
139	["benign","0.0316044",5,"Low","Uncertain","ABCA4-R943Q",true,"benign","Homozygous",-1]
140	["benign","0.0320692",4,"Low","Uncertain","KEL-T193M",true,"benign","Heterozygous",1]
141	["benign","0.0320692",4,"Low","Uncertain","KEL-T193M",true,"benign","Homozygous",1]
142	["benign","0.0333767",5,"Low","Uncertain","GFAP-D295N",true,"benign","Heterozygous",-1]
143	["benign","0.0333767",5,"Low","Uncertain","GFAP-D295N",true,"benign","Homozygous",-1]
144	["benign","0.0373134",3,"Low","Uncertain","SPTA1-A970D",true,"benign","Heterozygous",-1]
145	["benign","0.0373134",3,"Low","Uncertain","SPTA1-A970D",true,"benign","Homozygous",-1]
146	["benign","0.0374605",5,"Low","Uncertain","CBLC-H405Y",true,"benign","Heterozygous",-1]
147	["benign","0.0377394",2,"Low","Uncertain","PCCA-I475V",true,"benign","Heterozygous",-1]
148	["benign","0.0377394",2,"Low","Uncertain","PCCA-I475V",true,"benign","Homozygous",-1]
149	["benign","0.0377604",3,"Low","Uncertain","TXNDC3-I338T",true,"benign","Heterozygous",-1]
150	["benign","0.0377604",3,"Low","Uncertain","TXNDC3-I338T",true,"benign","Homozygous",-1]
151	["benign","0.0390625",4,"Low","Uncertain","GHRL-Q90L",true,"benign","Heterozygous",-1]
152	["benign","0.0400632",4,"Low","Uncertain","COL5A2-P460S",true,"benign","Heterozygous",-1]
153	["benign","0.0407139",4,"Low","Uncertain","COL7A1-P1277L",true,"benign","Heterozygous",-1]
154	["benign","0.0407139",4,"Low","Uncertain","COL7A1-P1277L",true,"benign","Homozygous",-1]
155	["benign","0.0420019",5,"Low","Uncertain","MAPT-Q230R",true,"benign","Heterozygous",-1]
156	["benign","0.042466",4,"Low","Uncertain","KRT85-R78H",true,"benign","Carrier (Heterozygous)",-1]
157	["benign","0.042466",4,"Low","Uncertain","KRT85-R78H",true,"benign","Homozygous",1]
158	["benign","0.0429448",3,"Low","Uncertain","NTRK1-G613V",true,"benign","Heterozygous",-1]
159	["benign","0.0430641",5,"Low","Likely","MYO7A-Y1719C",true,"benign","Heterozygous",-1]
160	["benign","0.0431307",5,"Low","Uncertain","NTRK1-H604Y",true,"benign","Heterozygous",-1]
161	["benign","0.0439673",3,"Low","Likely","EFHC1-R182H",true,"benign","Heterozygous",-1]
162	["benign","0.0439673",3,"Low","Likely","EFHC1-R182H",true,"benign","Homozygous",-1]
163	["benign","0.0441532",2,"Low","Uncertain","ABCA12-R287G",true,"benign","Heterozygous",-1]
164	["benign","0.0441778",4,"Low","Uncertain","TCIRG1-R56W",true,"benign","Heterozygous",-1]
165	["benign","0.0441778",4,"Low","Uncertain","TCIRG1-R56W",true,"benign","Homozygous",-1]
166	["benign","0.0448968",4,"Low","Uncertain","F5-D2222G",true,"benign","Heterozygous",-1]
167	["benign","0.0448968",4,"Low","Uncertain","F5-D2222G",true,"benign","Homozygous",-1]
168	["benign","0.0454545",5,"Low","Uncertain","WFS1-R456H",true,"benign","Heterozygous",-1]
169	["benign","0.0460123",5,"Low","Uncertain","VWF-G2705R",true,"benign","Heterozygous",-1]
170	["benign","0.0460123",5,"Low","Uncertain","VWF-G2705R",true,"benign","Homozygous",-1]
171	["benign","0.0462911",5,"Low","Uncertain","BRCA1-Q356R",true,"benign","Heterozygous",-1]
172	["benign","0.0462911",5,"Low","Uncertain","BRCA1-Q356R",true,"benign","Homozygous",-1]
173	["benign","0.0467559",5,"Low","Uncertain","DNAH5-P4488T",true,"benign","Heterozygous",-1]
174	["benign","0.0482432",5,"Low","Uncertain","CD19-R514H",true,"benign","Heterozygous",-1]
175	["benign","0.0482432",5,"Low","Uncertain","CD19-R514H",true,"benign","Homozygous",-1]
176	["benign","0.0484135",3,"Low","Uncertain","DYNC2H1-Q304L",true,"benign","Heterozygous",-1]
177	["benign","0.0484135",3,"Low","Uncertain","DYNC2H1-Q304L",true,"benign","Homozygous",-1]
178	["benign","0.048615",4,"Low","Likely","PKHD1-I3905N",true,"benign","Heterozygous",-1]
179	["benign","0.048615",4,"Low","Likely","PKHD1-I3905N",true,"benign","Homozygous",-1]
180	["benign","0.0507529",3,"Low","Likely","FANCI-P55L",true,"benign","Heterozygous",-1]
181	["benign","0.0507529",3,"Low","Likely","FANCI-P55L",true,"benign","Homozygous",-1]
182	["benign","0.0565161",5,"Low","Likely","OCA2-R419Q",true,"benign","Heterozygous",-1]
183	["benign","0.0565161",5,"Low","Likely","OCA2-R419Q",true,"benign","Homozygous",-1]
184	["benign","0.0570413",3,"Low","Likely","PKD1-A4059V",true,"benign","Heterozygous",-1]
185	["benign","0.0570413",3,"Low","Likely","PKD1-A4059V",true,"benign","Homozygous",-1]
186	["benign","0.0570738",4,"Low","Uncertain","FMO3-V257M",true,"benign","Heterozygous",-1]
187	["benign","0.0570738",4,"Low","Uncertain","FMO3-V257M",true,"benign","Homozygous",-1]
188	["benign","0.0580963",3,"Low","Uncertain","F5-M413T",true,"benign","Heterozygous",-1]
189	["benign","0.0580963",3,"Low","Uncertain","F5-M413T",true,"benign","Homozygous",-1]
190	["benign","0.0584681",3,"Low","Uncertain","FANCA-S1088F",true,"benign","Heterozygous",-1]
191	["benign","0.0584681",3,"Low","Uncertain","FANCA-S1088F",true,"benign","Homozygous",-1]
192	["benign","0.0635806",4,"Low","Likely","ADA-K80R",true,"benign","Carrier (Heterozygous)",-1]
193	["benign","0.0635806",4,"Low","Likely","ADA-K80R",true,"benign","Homozygous",1]
194	["benign","0.0678565",3,"Low","Likely","COL6A3-D2831H",true,"benign","Heterozygous",-1]
195	["benign","0.0678565",3,"Low","Likely","COL6A3-D2831H",true,"benign","Homozygous",-1]
196	["benign","0.0695297",3,"Low","Uncertain","ERCC6-R1230P",true,"benign","Heterozygous",-1]
197	["benign","0.0695297",3,"Low","Uncertain","ERCC6-R1230P",true,"benign","Homozygous",-1]
198	["benign","0.0716676",4,"Low","Uncertain","GALT-N314D",true,"benign","Heterozygous",-1]
199	["benign","0.0716676",4,"Low","Uncertain","GALT-N314D",true,"benign","Homozygous",-1]
200	["benign","0.0725056",3,"Low","Likely","FLT4-N149D",true,"benign","Heterozygous",-1]
201	["benign","0.0725056",3,"Low","Likely","FLT4-N149D",true,"benign","Homozygous",-1]
202	["benign","0.072876",3,"Low","Uncertain","ELN-G581R",true,"benign","Heterozygous",-1]
203	["benign","0.072876",3,"Low","Uncertain","ELN-G581R",true,"benign","Homozygous",-1]
204	["benign","0.0778026",4,"Low","Uncertain","RAPSN-R58C",true,"benign","Heterozygous",-1]
205	["benign","0.0778026",4,"Low","Uncertain","RAPSN-R58C",true,"benign","Homozygous",-1]
206	["benign","0.0779885",2,"Low","Uncertain","FBN2-S2580L",true,"benign","Heterozygous",1]
207	["benign","0.0779885",2,"Low","Uncertain","FBN2-S2580L",true,"benign","Homozygous",1]
208	["benign","0.0791039",3,"Low","Likely","EVC-R443Q",true,"benign","Heterozygous",0]
209	["benign","0.0815207",5,"Low","Likely","OCA2-R305W",true,"benign","Heterozygous",-1]
210	["benign","0.0940695",3,"Low","Uncertain","AMPD1-P48L",true,"benign","Heterozygous",-1]
211	["benign","0.0940695",3,"Low","Uncertain","AMPD1-P48L",true,"benign","Homozygous",-1]
212	["benign","0.0969511",2,"Low","Uncertain","HR-T1022A",true,"benign","Carrier (Heterozygous)",-1]
213	["benign","0.0976947",3,"Low","Uncertain","ABCC11-G180R",true,"benign","Heterozygous",-1]
214	["benign","0.0976947",3,"Low","Uncertain","ABCC11-G180R",true,"benign","Homozygous",-1]
215	["benign","0.108849",3,"Low","Uncertain","FLG-R3530S",true,"benign","Heterozygous",-1]
216	["benign","0.111835",4,"Low","Likely","NOTCH3-A1020P",true,"benign","Heterozygous",-1]
217	["benign","0.140387",3,"Low","Uncertain","THBD-A473V",true,"benign","Heterozygous",-1]
218	["benign","0.140387",3,"Low","Uncertain","THBD-A473V",true,"benign","Homozygous",-1]
219	["benign","0.143045",2,"Low","Uncertain","DSPP-R68W",true,"benign","Heterozygous",-1]
220	["benign","0.143045",2,"Low","Uncertain","DSPP-R68W",true,"benign","Homozygous",-1]
221	["benign","0.155326",4,"Low","Uncertain","PHYH-P29S",true,"benign","Heterozygous",-1]
222	["benign","0.155326",4,"Low","Uncertain","PHYH-P29S",true,"benign","Homozygous",-1]
223	["benign","0.155549",4,"Low","Uncertain","MAPT-R370W",true,"benign","Heterozygous",-1]
224	["benign","0.155549",4,"Low","Uncertain","MAPT-R370W",true,"benign","Homozygous",-1]
225	["benign","0.183199",4,"Low","Well-established","ARSA-N350S",true,"benign","Heterozygous",-1]
226	["benign","0.183199",4,"Low","Well-established","ARSA-N350S",true,"benign","Homozygous",-1]
227	["benign","0.204964",5,"Low","Well-established","TYR-R402Q",true,"benign","Heterozygous",0]
228	["benign","0.204964",5,"Low","Well-established","TYR-R402Q",true,"benign","Homozygous",0]
229	["benign","0.21016",4,"Low","Uncertain","GUCY2D-A52S",true,"benign","Carrier (Heterozygous)",-1]
230	["benign","0.21016",4,"Low","Uncertain","GUCY2D-A52S",true,"benign","Homozygous",1]
231	["benign","0.221231",3,"Low","Uncertain","PKP2-L366P",true,"benign","Heterozygous",-1]
232	["benign","0.221231",3,"Low","Uncertain","PKP2-L366P",true,"benign","Homozygous",-1]
233	["benign","0.232202",4,"Low","Uncertain","RPGRIP1-A547S",true,"benign","Heterozygous",0]
234	["benign","0.232202",4,"Low","Uncertain","RPGRIP1-A547S",true,"benign","Homozygous",0]
235	["benign","0.239822",3,"Low","Uncertain","MLH1-I219V",true,"benign","Heterozygous",1]
236	["benign","0.239822",3,"Low","Uncertain","MLH1-I219V",true,"benign","Homozygous",1]
237	["benign","0.255899",3,"Low","Uncertain","LOXL1-R141L",true,"benign","Heterozygous",0]
238	["benign","0.255899",3,"Low","Uncertain","LOXL1-R141L",true,"benign","Homozygous",0]
239	["benign","0.270682",5,"Low","Uncertain","TYR-S192Y",true,"benign","Heterozygous",-1]
240	["benign","0.270682",5,"Low","Uncertain","TYR-S192Y",true,"benign","Homozygous",-1]
241	["benign","0.27282",3,"Low","Likely","CACNA1S-L458H",true,"benign","Heterozygous",-1]
242	["benign","0.27282",3,"Low","Likely","CACNA1S-L458H",true,"benign","Homozygous",-1]
243	["benign","0.286166",2,"Low","Uncertain","TPCN2-G734E",true,"benign","Heterozygous",-1]
244	["benign","0.286166",2,"Low","Uncertain","TPCN2-G734E",true,"benign","Homozygous",-1]
245	["benign","0.29631",4,"Low","Uncertain","PTCH1-P1315L",true,"benign","Heterozygous",-1]
246	["benign","0.29631",4,"Low","Uncertain","PTCH1-P1315L",true,"benign","Homozygous",-1]
247	["benign","0.348671",4,"Low","Uncertain","RP1-N985Y",true,"benign","Heterozygous",-1]
248	["benign","0.348671",4,"Low","Uncertain","RP1-N985Y",true,"benign","Homozygous",-1]
249	["benign","0.374884",3,"Low","Likely","PMS2-P470S",true,"benign","Heterozygous",-1]
250	["benign","0.374884",3,"Low","Likely","PMS2-P470S",true,"benign","Homozygous",-1]
251	["benign","0.431121",4,"Low","Uncertain","TAS2R38-A49P",true,"benign","Heterozygous",-1]
252	["benign","0.431121",4,"Low","Uncertain","TAS2R38-A49P",true,"benign","Homozygous",-1]
253	["benign","0.463376",5,"Low","Uncertain","TAS2R38-I296V",true,"benign","Heterozygous",-1]
254	["benign","0.463376",5,"Low","Uncertain","TAS2R38-I296V",true,"benign","Homozygous",-1]
255	["benign","0.691764",5,"Low","Uncertain","SLC45A2-L374F",true,"benign","Heterozygous",-1]
256	["benign","0.691764",5,"Low","Uncertain","SLC45A2-L374F",true,"benign","Homozygous",-1]
257	["benign","0.888269",2,"Low","Uncertain","PCSK9-G670E",true,"benign","Heterozygous",-1]
258	["benign","0.888269",2,"Low","Uncertain","PCSK9-G670E",true,"benign","Homozygous",-1]
259	["benign","0.999628",2,"Low","Uncertain","APOB-Y1422C",true,"benign","Homozygous",-1]
260	["benign","",1,"Low","Likely","SERPINA3-P252A",true,"benign","Heterozygous",-1]
261	["benign","",1,"Low","Uncertain","MED25-A335V",true,"benign","Carrier (Heterozygous)",-1]
262	["benign","",1,"Low","Uncertain","RXFP2-T222P",true,"benign","Heterozygous",-1]
263	["benign","",2,"Low","Likely","JAK3-P151R",true,"benign","Heterozygous",-1]
264	["benign","",2,"Low","Likely","KCNQ3-P574S",true,"benign","Heterozygous",-1]
265	["benign","",2,"Low","Likely","NLRP3-V200M",true,"benign","Heterozygous",-1]
266	["benign","",2,"Low","Uncertain","LRP2-D2054N",true,"benign","Heterozygous",-1]
267	["benign","",3,"Low","Likely","ANG-K41I",true,"benign","Heterozygous",-1]
268	["benign","",3,"Low","Likely","ATRX-N1860S",true,"benign","Heterozygous",-1]
269	["benign","",3,"Low","Likely","ATRX-N1860S",true,"benign","Homozygous",-1]
270	["benign","",3,"Low","Likely","COL6A3-E1386K",true,"benign","Heterozygous",-1]
271	["benign","",3,"Low","Likely","LDB3-S189L",true,"benign","Heterozygous",-1]
272	["benign","",3,"Low","Likely","MYBPC3-T957S",true,"benign","Heterozygous",-1]
273	["benign","",3,"Low","Likely","SCN5A-V789I",true,"benign","Heterozygous",-1]
274	["benign","",3,"Low","Uncertain","DSG2-V56M",true,"benign","Heterozygous",-1]
275	["benign","",3,"Low","Well-established","LRRK2-A419V",true,"benign","Heterozygous",-1]
276	["benign","",4,"Low","Likely","GJB3-A194T",true,"benign","Heterozygous",-1]
277	["benign","",4,"Low","Likely","NEFL-S472Shift",true,"benign","Homozygous",-1]
278	["benign","",6,"Low","Uncertain","TNNI3-P82S",true,"benign","Heterozygous",1]
279	["benign","9.2954e-05",3,"Low","Uncertain","KCNQ3-R777Q",true,"benign","Heterozygous",-1]
280	["benign","9.6283e-05",4,"Low","Uncertain","PKD1-G3300R",true,"benign","Heterozygous",-1]
281	["not reviewed","0.0886782",4,"Moderate","Uncertain","PPARG-P12A",true,"not reviewed","Heterozygous",-1]
282	["not reviewed","0.0886782",4,"Moderate","Uncertain","PPARG-P12A",true,"not reviewed","Homozygous",-1]
283	["not reviewed","0.400446",4,"Low","Uncertain","WFS1-R611H",true,"not reviewed","Carrier (Heterozygous)",-1]
284	["not reviewed","0.400446",4,"Low","Uncertain","WFS1-R611H",true,"not reviewed","Homozygous",1]
285	["not reviewed","",4,"High","Uncertain","PPT1-M57Shift",true,"not reviewed","Heterozygous",-1]
286	["pathogenic","0.000092954",4,"High","Well-established","DLD-G229C",true,"pathogenic","Carrier (Heterozygous)",-1]
287	["pathogenic","0.000092954",5,"High","Uncertain","RAG2-G95R",true,"pathogenic","Carrier (Heterozygous)",-1]
288	["pathogenic","0.000092954",5,"Moderate","Uncertain","GDAP1-L239F",true,"pathogenic","Carrier (Heterozygous)",-1]
289	["pathogenic","0.000092954",6,"High","Likely","GNRHR-R139H",true,"pathogenic","Carrier (Heterozygous)",-1]
290	["pathogenic","0.000092954",6,"High","Likely","HEXA-R504C",true,"pathogenic","Carrier (Heterozygous)",-1]
291	["pathogenic","0.000092954",6,"Moderate","Uncertain","TYR-M1V",true,"pathogenic","Carrier (Heterozygous)",-1]
292	["pathogenic","0.000185908",3,"Moderate","Uncertain","SNCB-P123H",true,"pathogenic","Heterozygous",1]
293	["pathogenic","0.000185908",4,"High","Uncertain","ABCG8-R543S",true,"pathogenic","Carrier (Heterozygous)",-1]
294	["pathogenic","0.000185908",4,"High","Uncertain","FAM126A-Q154R",true,"pathogenic","Carrier (Heterozygous)",-1]
295	["pathogenic","0.000185908",4,"High","Uncertain","PMP22-Y136S",true,"pathogenic","Carrier (Heterozygous)",-1]
296	["pathogenic","0.000185908",5,"High","Uncertain","MYL2-A13T",true,"pathogenic","Heterozygous",1]
297	["pathogenic","0.000185908",5,"High","Well-established","ABCA4-P1380L",true,"pathogenic","Carrier (Heterozygous)",-1]
298	["pathogenic","0.000185908",6,"High","Uncertain","MFN2-R707W",true,"pathogenic","Carrier (Heterozygous)",-1]
299	["pathogenic","0.000185908",6,"Moderate","Uncertain","ATP1A2-R65W",true,"pathogenic","Heterozygous",1]
300	["pathogenic","0.000198333",4,"High","Uncertain","CACNA1C-G490R",true,"pathogenic","Heterozygous",1]
301	["pathogenic","0.000278862",5,"High","Uncertain","CIRH1A-R565W",true,"pathogenic","Carrier (Heterozygous)",-1]
302	["pathogenic","0.000278862",5,"Moderate","Likely","BTD-A171T",true,"pathogenic","Carrier (Heterozygous)",-1]
303	["pathogenic","0.000278862",6,"High","Uncertain","BRIP1-P47A",true,"pathogenic","Heterozygous",1]
304	["pathogenic","0.000278914",4,"High","Well-established","JAK2-V617F",true,"pathogenic","Heterozygous",1]
305	["pathogenic","0.00028409",6,"High","Uncertain","VHL-P81S",true,"pathogenic","Heterozygous",1]
306	["pathogenic","0.000292283",4,"High","Uncertain","SCN5A-G615E",true,"pathogenic","Heterozygous",1]
307	["pathogenic","0.000297265",4,"High","Uncertain","STXBP2-R190C",true,"pathogenic","Carrier (Heterozygous)",-1]
308	["pathogenic","0.000371816",4,"Moderate","Uncertain","LDLR-V827I",true,"pathogenic","Heterozygous",1]
309	["pathogenic","0.000371816",5,"High","Uncertain","ABCA4-P1780A",true,"pathogenic","Carrier (Heterozygous)",-1]
310	["pathogenic","0.000371816",5,"High","Uncertain","KCNE2-I57T",true,"pathogenic","Heterozygous",1]
311	["pathogenic","0.000371816",6,"High","Well-established","PAH-Y414C",true,"pathogenic","Carrier (Heterozygous)",-1]
312	["pathogenic","0.000375657",4,"High","Uncertain","WNK4-R1185C",true,"pathogenic","Heterozygous",1]
313	["pathogenic","0.000456986",4,"High","Uncertain","FGD1-P312L",true,"pathogenic","Carrier (Heterozygous)",-1]
314	["pathogenic","0.00046477",4,"Low","Uncertain","PRODH-A455S",true,"pathogenic","Heterozygous",-1]
315	["pathogenic","0.00046477",5,"Moderate","Well-established","LRRK2-G2019S",true,"pathogenic","Heterozygous",-1]
316	["pathogenic","0.00046477",6,"Moderate","Uncertain","FMO3-R492W",true,"pathogenic","Carrier (Heterozygous)",-1]
317	["pathogenic","0.000506585",4,"High","Uncertain","CC2D2A-G776R",true,"pathogenic","Carrier (Heterozygous)",-1]
318	["pathogenic","0.000557724",3,"Moderate","Likely","F11-E135X",true,"pathogenic","Carrier (Heterozygous)",-1]
319	["pathogenic","0.000557724",4,"Low","Uncertain","MPO-Y173C",true,"pathogenic","Carrier (Heterozygous)",-1]
320	["pathogenic","0.000557724",5,"High","Uncertain","ACTN2-Q9R",true,"pathogenic","Heterozygous",1]
321	["pathogenic","0.000558035",4,"High","Uncertain","STRA6-T321P",true,"pathogenic","Carrier (Heterozygous)",-1]
322	["pathogenic","0.000558451",4,"Low","Uncertain","AIP-R304Q",true,"pathogenic","Heterozygous",1]
323	["pathogenic","0.000650678",2,"Moderate","Likely","CYP24A1-R396W",true,"pathogenic","Carrier (Heterozygous)",-1]
324	["pathogenic","0.000650678",6,"Low","Uncertain","PAH-V245A",true,"pathogenic","Carrier (Heterozygous)",-1]
325	["pathogenic","0.000652619",6,"High","Well-established","IDUA-Q70X",true,"pathogenic","Carrier (Heterozygous)",-1]
326	["pathogenic","0.000743632",4,"Moderate","Likely","UGT1A1-G71R",true,"pathogenic","Heterozygous",0]
327	["pathogenic","0.000743632",4,"Moderate","Likely","UGT1A1-G71R",true,"pathogenic","Homozygous",0]
328	["pathogenic","0.000743632",6,"Moderate","Well-established","CLCN1-R894X",true,"pathogenic","Heterozygous",0]
329	["pathogenic","0.000836586",5,"High","Uncertain","CDH15-A122V",true,"pathogenic","Heterozygous",1]
330	["pathogenic","0.000836586",5,"High","Uncertain","CRB1-V162M",true,"pathogenic","Heterozygous",1]
331	["pathogenic","0.000836586",6,"High","Likely","RAPSN-N88K",true,"pathogenic","Carrier (Heterozygous)",-1]
332	["pathogenic","0.000836586",6,"Low","Uncertain","PSEN2-S130L",true,"pathogenic","Heterozygous",1]
333	["pathogenic","0.000839865",5,"High","Likely","TSEN54-A307S",true,"pathogenic","Carrier (Heterozygous)",-1]
334	["pathogenic","0.00092954",6,"High","Well-established","CPT2-S113L",true,"pathogenic","Carrier (Heterozygous)",-1]
335	["pathogenic","0.00102249",3,"Moderate","Likely","EPHA2-R721Q",true,"pathogenic","Heterozygous",1]
336	["pathogenic","0.00102249",4,"High","Uncertain","MTR-P749S",true,"pathogenic","Heterozygous",-1]
337	["pathogenic","0.00111545",3,"High","Uncertain","GPD1L-I124V",true,"pathogenic","Heterozygous",1]
338	["pathogenic","0.00112045",4,"High","Uncertain","THBD-P495S",true,"pathogenic","Heterozygous",1]
339	["pathogenic","0.0012084",4,"Moderate","Uncertain","WFS1-C426Y",true,"pathogenic","Heterozygous",1]
340	["pathogenic","0.00130136",2,"Low","Uncertain","BMP4-R287H",true,"pathogenic","Heterozygous",1]
341	["pathogenic","0.00130136",5,"Low","Uncertain","RET-Y791F",true,"pathogenic","Heterozygous",-1]
342	["pathogenic","0.00130136",6,"High","Likely","CFTR-R117H",true,"pathogenic","Carrier (Heterozygous)",-1]
343	["pathogenic","0.00148726",3,"High","Uncertain","SI-G1073D",true,"pathogenic","Carrier (Heterozygous)",-1]
344	["pathogenic","0.00148726",6,"Low","Uncertain","OCA2-A481T",true,"pathogenic","Carrier (Heterozygous)",-1]
345	["pathogenic","0.00148726",6,"Moderate","Likely","GJB2-V37I",true,"pathogenic","Carrier (Heterozygous)",-1]
346	["pathogenic","0.00148754",4,"High","Likely","SQSTM1-P392L",true,"pathogenic","Heterozygous",1]
347	["pathogenic","0.00149617",6,"Moderate","Uncertain","CYP1B1-R368H",true,"pathogenic","Carrier (Heterozygous)",-1]
348	["pathogenic","0.00167317",6,"High","Well-established","CFTR-G542X",true,"pathogenic","Carrier (Heterozygous)",-1]
349	["pathogenic","0.00167317",6,"High","Well-established","GALT-Q188R",true,"pathogenic","Carrier (Heterozygous)",-1]
350	["pathogenic","0.00176613",5,"High","Uncertain","POLG-G737R",true,"pathogenic","Carrier (Heterozygous)",-1]
351	["pathogenic","0.00176613",6,"Moderate","Well-established","BBS1-M390R",true,"pathogenic","Carrier (Heterozygous)",-1]
352	["pathogenic","0.00195204",4,"High","Uncertain","TREM2-R47H",true,"pathogenic","Carrier (Heterozygous)",-1]
353	["pathogenic","0.00195204",5,"High","Uncertain","FBN1-R1170H",true,"pathogenic","Heterozygous",1]
354	["pathogenic","0.00195204",5,"Low","Likely","CTRC-R254W",true,"pathogenic","Heterozygous",1]
355	["pathogenic","0.00195204",5,"Low","Uncertain","HAMP-G71D",true,"pathogenic","Carrier (Heterozygous)",-1]
356	["pathogenic","0.00195204",6,"High","Well-established","PYGM-R50X",true,"pathogenic","Carrier (Heterozygous)",-1]
357	["pathogenic","0.00200401",4,"High","Uncertain","PKD1-R4276W",true,"pathogenic","Heterozygous",1]
358	["pathogenic","0.00213794",5,"Moderate","Well-established","SLC3A1-M467T",true,"pathogenic","Carrier (Heterozygous)",-1]
359	["pathogenic","0.00213794",5,"Moderate","Well-established","SLC3A1-M467T",true,"pathogenic","Homozygous",1]
360	["pathogenic","0.0022309",4,"Moderate","Uncertain","ACY1-R353C",true,"pathogenic","Carrier (Heterozygous)",-1]
361	["pathogenic","0.0022309",6,"Moderate","Uncertain","FMO3-P153L",true,"pathogenic","Carrier (Heterozygous)",-1]
362	["pathogenic","0.00232385",4,"Moderate","Uncertain","RHO-G51A",true,"pathogenic","Heterozygous",1]
363	["pathogenic","0.00232385",6,"Low","Uncertain","TFR2-R455Q",true,"pathogenic","Heterozygous",-1]
364	["pathogenic","0.00232385",6,"Moderate","Likely","VWF-Y1584C",true,"pathogenic","Heterozygous",1]
365	["pathogenic","0.00241681",4,"Low","Uncertain","PKP2-S140F",true,"pathogenic","Heterozygous",1]
366	["pathogenic","0.00260271",4,"High","Uncertain","SERPINA1-R247C",true,"pathogenic","Carrier (Heterozygous)",-1]
367	["pathogenic","0.00260271",5,"High","Uncertain","PKD2-S804N",true,"pathogenic","Heterozygous",1]
368	["pathogenic","0.00267533",6,"Low","Uncertain","TERT-H412Y",true,"pathogenic","Heterozygous",1]
369	["pathogenic","0.00269567",4,"Moderate","Uncertain","PITPNM3-Q626H",true,"pathogenic","Heterozygous",1]
370	["pathogenic","0.00269567",5,"High","Likely","ABCA4-G1961E",true,"pathogenic","Carrier (Heterozygous)",-1]
371	["pathogenic","0.00288158",4,"High","Likely","CBS-I278T",true,"pathogenic","Carrier (Heterozygous)",-1]
372	["pathogenic","0.00288158",4,"High","Uncertain","PEX26-Y109H",true,"pathogenic","Carrier (Heterozygous)",-1]
373	["pathogenic","0.00288158",5,"High","Uncertain","ALOXE3-L237M",true,"pathogenic","Carrier (Heterozygous)",-1]
374	["pathogenic","0.00288158",5,"High","Uncertain","GNRHR-Q106R",true,"pathogenic","Carrier (Heterozygous)",-1]
375	["pathogenic","0.00288158",5,"Low","Uncertain","RNASEL-E265X",true,"pathogenic","Heterozygous",1]
376	["pathogenic","0.00325339",4,"Moderate","Uncertain","SLC7A9-A182T",true,"pathogenic","Carrier (Heterozygous)",-1]
377	["pathogenic","0.0034393",4,"Moderate","Uncertain","SLC9A3R1-R153Q",true,"pathogenic","Heterozygous",1]
378	["pathogenic","0.00353291",5,"Moderate","Uncertain","SLC26A4-I300L",true,"pathogenic","Carrier (Heterozygous)",-1]
379	["pathogenic","0.00356043",4,"Low","Uncertain","MAD1L1-R59C",true,"pathogenic","Heterozygous",-1]
380	["pathogenic","0.00362521",4,"Moderate","Uncertain","SPG7-A510V",true,"pathogenic","Carrier (Heterozygous)",-1]
381	["pathogenic","0.00365206",2,"High","Uncertain","PRPH-D141Y",true,"pathogenic","Carrier (Heterozygous)",-1]
382	["pathogenic","0.00371816",5,"High","Uncertain","ABCA4-V2050L",true,"pathogenic","Carrier (Heterozygous)",-1]
383	["pathogenic","0.00383583",4,"High","Uncertain","THBD-A43T",true,"pathogenic","Heterozygous",1]
384	["pathogenic","0.00390407",6,"Low","Likely","CSRP3-W4R",true,"pathogenic","Heterozygous",-1]
385	["pathogenic","0.00399703",6,"Low","Uncertain","TNFRSF13B-C104R",true,"pathogenic","Heterozygous",1]
386	["pathogenic","0.00400223",5,"High","Uncertain","PMM2-R141H",true,"pathogenic","Carrier (Heterozygous)",-1]
387	["pathogenic","0.00408998",6,"Moderate","Likely","VWF-R854Q",true,"pathogenic","Carrier (Heterozygous)",-1]
388	["pathogenic","0.00409074",4,"Low","Likely","PDE11A-R307X",true,"pathogenic","Heterozygous",-1]
389	["pathogenic","0.00409074",4,"Low","Likely","PDE11A-R307X",true,"pathogenic","Homozygous",-1]
390	["pathogenic","0.00427589",5,"High","Uncertain","CAV3-T78M",true,"pathogenic","Heterozygous",1]
391	["pathogenic","0.00436884",4,"Low","Uncertain","PRODH-L289M",true,"pathogenic","Heterozygous",-1]
392	["pathogenic","0.00436884",5,"High","Uncertain","CFH-Q950H",true,"pathogenic","Heterozygous",1]
393	["pathogenic","0.00474066",1,"Moderate","Uncertain","MYO1A-S797F",true,"pathogenic","Heterozygous",1]
394	["pathogenic","0.00474684",5,"High","Likely","CFTR-G576A",true,"pathogenic","Carrier (Heterozygous)",-1]
395	["pathogenic","0.00492657",5,"High","Well-established","ABCA4-G863A",true,"pathogenic","Carrier (Heterozygous)",-1]
396	["pathogenic","0.00501952",6,"Low","Uncertain","MEFV-R408Q",true,"pathogenic","Carrier (Heterozygous)",-1]
397	["pathogenic","0.00511247",6,"Low","Uncertain","MEFV-P369S",true,"pathogenic","Carrier (Heterozygous)",-1]
398	["pathogenic","0.00529838",4,"Moderate","Uncertain","CFTR-S1235R",true,"pathogenic","Carrier (Heterozygous)",-1]
399	["pathogenic","0.00529838",4,"Moderate","Uncertain","CFTR-S1235R",true,"pathogenic","Homozygous",1]
400	["pathogenic","0.00548429",4,"Low","Uncertain","GLI3-G727R",true,"pathogenic","Heterozygous",1]
401	["pathogenic","0.00558552",4,"High","Uncertain","DOK7-S45L",true,"pathogenic","Carrier (Heterozygous)",-1]
402	["pathogenic","0.00594906",4,"High","Well-established","PRODH-L441P",true,"pathogenic","Carrier (Heterozygous)",-1]
403	["pathogenic","0.00623024",4,"Low","Uncertain","ATM-D814E",true,"pathogenic","Heterozygous",0]
404	["pathogenic","0.00641383",4,"Low","Uncertain","SCNN1G-E197K",true,"pathogenic","Heterozygous",1]
405	["pathogenic","0.00641502",5,"Moderate","Uncertain","TGM1-E520G",true,"pathogenic","Carrier (Heterozygous)",-1]
406	["pathogenic","0.00706451",4,"Low","Uncertain","SLC5A2-N654S",true,"pathogenic","Carrier (Heterozygous)",-1]
407	["pathogenic","0.00715746",3,"Low","Uncertain","FANCG-R513Q",true,"pathogenic","Heterozygous",1]
408	["pathogenic","0.00743633",4,"Low","Likely","MSR1-R293X",true,"pathogenic","Heterozygous",1]
409	["pathogenic","0.0078125",3,"Moderate","Uncertain","FIG4-K278Shift",true,"pathogenic","Carrier (Heterozygous)",-1]
410	["pathogenic","0.0078125",4,"High","Uncertain","ACADVL-R385W",true,"pathogenic","Carrier (Heterozygous)",-1]
411	["pathogenic","0.0078125",4,"High","Uncertain","CBS-T460M",true,"pathogenic","Carrier (Heterozygous)",-1]
412	["pathogenic","0.0078125",4,"High","Uncertain","SPG7-G199Shift",true,"pathogenic","Carrier (Heterozygous)",-1]
413	["pathogenic","0.0078125",4,"Moderate","Uncertain","CASP10-I185R",true,"pathogenic","Heterozygous",1]
414	["pathogenic","0.0078125",4,"Moderate","Uncertain","TGM1-Y312Shift",true,"pathogenic","Carrier (Heterozygous)",-1]
415	["pathogenic","0.0078125",5,"Moderate","Uncertain","SCN5A-R1193Q",true,"pathogenic","Heterozygous",1]
416	["pathogenic","0.00793651",4,"Moderate","Uncertain","FLG-S761Shift",true,"pathogenic","Heterozygous",0]
417	["pathogenic","0.00799405",4,"High","Uncertain","PEX2-W250R",true,"pathogenic","Carrier (Heterozygous)",-1]
418	["pathogenic","0.00806452",4,"Moderate","Uncertain","TGM1-A700P",true,"pathogenic","Carrier (Heterozygous)",-1]
419	["pathogenic","0.00817996",5,"Low","Well-established","CTH-T67I",true,"pathogenic","Carrier (Heterozygous)",-1]
420	["pathogenic","0.00862069",2,"High","Uncertain","SLX4-G1396Shift",true,"pathogenic","Carrier (Heterozygous)",-1]
421	["pathogenic","0.00873768",4,"High","Uncertain","KCNE1-D85N",true,"pathogenic","Heterozygous",-1]
422	["pathogenic","0.00873768",4,"High","Uncertain","KCNE1-D85N",true,"pathogenic","Homozygous",-1]
423	["pathogenic","0.00883228",5,"Moderate","Uncertain","APC-E1317Q",true,"pathogenic","Heterozygous",1]
424	["pathogenic","0.0091095",4,"Low","Uncertain","MPO-M251T",true,"pathogenic","Carrier (Heterozygous)",-1]
425	["pathogenic","0.00976018",5,"Low","Uncertain","HFE-S65C",true,"pathogenic","Carrier (Heterozygous)",-1]
426	["pathogenic","0.00994609",5,"Moderate","Well-established","GJB2-M34T",true,"pathogenic","Carrier (Heterozygous)",-1]
427	["pathogenic","0.00995349",5,"Low","Uncertain","ATM-S49C",true,"pathogenic","Heterozygous",0]
428	["pathogenic","0.00995349",5,"Low","Uncertain","ATM-S49C",true,"pathogenic","Homozygous",0]
429	["pathogenic","0.010132",4,"Low","Uncertain","PRODH-R453C",true,"pathogenic","Carrier (Heterozygous)",-1]
430	["pathogenic","0.0104109",4,"High","Uncertain","SPG11-K1013E",true,"pathogenic","Carrier (Heterozygous)",-1]
431	["pathogenic","0.0105116",4,"Moderate","Uncertain","PHKB-M185I",true,"pathogenic","Carrier (Heterozygous)",-1]
432	["pathogenic","0.0106698",6,"Moderate","Uncertain","MATN3-T303M",true,"pathogenic","Heterozygous",-1]
433	["pathogenic","0.0106897",4,"Low","Likely","NOD2-G908R",true,"pathogenic","Heterozygous",-1]
434	["pathogenic","0.0109223",3,"Low","Likely","LMNB2-R215Q",true,"pathogenic","Heterozygous",1]
435	["pathogenic","0.0109223",3,"Low","Likely","LMNB2-R215Q",true,"pathogenic","Homozygous",1]
436	["pathogenic","0.0114142",4,"Low","Uncertain","CD40LG-G219R",true,"pathogenic","Carrier (Heterozygous)",-1]
437	["pathogenic","0.0114142",4,"Low","Uncertain","CD40LG-G219R",true,"pathogenic","Homozygous",1]
438	["pathogenic","0.0117122",5,"High","Well-established","SERPINA1-E366K",true,"pathogenic","Carrier (Heterozygous)",-1]
439	["pathogenic","0.0117122",5,"High","Well-established","SERPINA1-E366K",true,"pathogenic","Homozygous",1]
440	["pathogenic","0.0118052",3,"Moderate","Uncertain","SLC4A1-E40K",true,"pathogenic","Carrier (Heterozygous)",-1]
441	["pathogenic","0.0119003",5,"High","Uncertain","RP1-T373I",true,"pathogenic","Carrier (Heterozygous)",-1]
442	["pathogenic","0.0119003",5,"High","Uncertain","RP1-T373I",true,"pathogenic","Homozygous",1]
443	["pathogenic","0.0120929",6,"Moderate","Uncertain","MEFV-E148Q",true,"pathogenic","Carrier (Heterozygous)",-1]
444	["pathogenic","0.0120929",6,"Moderate","Uncertain","MEFV-E148Q",true,"pathogenic","Homozygous",1]
445	["pathogenic","0.0133854",6,"Moderate","Well-established","FLG-R501X",true,"pathogenic","Carrier (Heterozygous)",-1]
446	["pathogenic","0.0134783",3,"Moderate","Uncertain","LPL-N318S",true,"pathogenic","Heterozygous",1]
447	["pathogenic","0.0140361",3,"High","Well-established","HBB-E7V",true,"pathogenic","Carrier (Heterozygous)",-1]
448	["pathogenic","0.0153374",4,"High","Likely","KLF11-T220M",true,"pathogenic","Heterozygous",1]
449	["pathogenic","0.016174",6,"Low","Uncertain","RET-R982C",true,"pathogenic","Heterozygous",1]
450	["pathogenic","0.0168247",5,"Low","Likely","DRD2-S311C",true,"pathogenic","Heterozygous",1]
451	["pathogenic","0.0168247",5,"Low","Likely","DRD2-S311C",true,"pathogenic","Homozygous",1]
452	["pathogenic","0.018312",3,"Low","Uncertain","ACAD8-S171C",true,"pathogenic","Carrier (Heterozygous)",-1]
453	["pathogenic","0.0187907",4,"Moderate","Well-established","WNT10A-F228I",true,"pathogenic","Heterozygous",-1]
454	["pathogenic","0.0187907",4,"Moderate","Well-established","WNT10A-F228I",true,"pathogenic","Homozygous",-1]
455	["pathogenic","0.0200781",3,"High","Uncertain","AIPL1-T114I",true,"pathogenic","Carrier (Heterozygous)",-1]
456	["pathogenic","0.0209147",4,"Low","Uncertain","KDR-C482R",true,"pathogenic","Heterozygous",0]
457	["pathogenic","0.0234375",2,"Moderate","Uncertain","FCN3-L117Shift",true,"pathogenic","Carrier (Heterozygous)",-1]
458	["pathogenic","0.0257483",2,"Moderate","Uncertain","MYO1A-G662E",true,"pathogenic","Heterozygous",1]
459	["pathogenic","0.0264887",5,"High","Uncertain","RPGRIP1-D1114G",true,"pathogenic","Carrier (Heterozygous)",-1]
460	["pathogenic","0.0270547",4,"High","Uncertain","PEX1-I696M",true,"pathogenic","Carrier (Heterozygous)",-1]
461	["pathogenic","0.0270547",4,"High","Uncertain","PEX1-I696M",true,"pathogenic","Homozygous",1]
462	["pathogenic","0.0276074",3,"Low","Uncertain","ELAC2-A541T",true,"pathogenic","Heterozygous",-1]
463	["pathogenic","0.0276074",3,"Low","Uncertain","ELAC2-A541T",true,"pathogenic","Homozygous",-1]
464	["pathogenic","0.0280721",5,"Moderate","Likely","HABP2-G534E",true,"pathogenic","Heterozygous",-1]
465	["pathogenic","0.0298383",5,"Low","Well-established","BTD-D444H",true,"pathogenic","Carrier (Heterozygous)",-1]
466	["pathogenic","0.0298383",5,"Low","Well-established","BTD-D444H",true,"pathogenic","Homozygous",1]
467	["pathogenic","0.0304889",5,"Low","Well-established","SERPINA1-E288V",true,"pathogenic","Carrier (Heterozygous)",-1]
468	["pathogenic","0.0325339",6,"Low","Likely","PRF1-A91V",true,"pathogenic","Heterozygous",0]
469	["pathogenic","0.0325339",6,"Low","Likely","PRF1-A91V",true,"pathogenic","Homozygous",0]
470	["pathogenic","0.0334821",5,"Low","Likely","NOD2-R702W",true,"pathogenic","Heterozygous",0]
471	["pathogenic","0.0334821",5,"Low","Likely","NOD2-R702W",true,"pathogenic","Homozygous",0]
472	["pathogenic","0.0356014",5,"Low","Uncertain","CPN1-G178D",true,"pathogenic","Carrier (Heterozygous)",-1]
473	["pathogenic","0.0356014",5,"Low","Uncertain","CPN1-G178D",true,"pathogenic","Homozygous",1]
474	["pathogenic","0.0381112",6,"High","Uncertain","CAV3-G56S",true,"pathogenic","Carrier (Heterozygous)",-1]
475	["pathogenic","0.0381112",6,"High","Uncertain","CAV3-G56S",true,"pathogenic","Homozygous",1]
476	["pathogenic","0.0388548",5,"Low","Likely","CETP-A390P",true,"pathogenic","Heterozygous",-1]
477	["pathogenic","0.0400632","","Moderate","Uncertain","SIAE-M89V",true,"pathogenic","Carrier (Heterozygous)",-1]
478	["pathogenic","0.0400632","","Moderate","Uncertain","SIAE-M89V",true,"pathogenic","Homozygous",1]
479	["pathogenic","0.0413646",6,"High","Uncertain","LRP5-V667M",true,"pathogenic","Carrier (Heterozygous)",-1]
480	["pathogenic","0.0413646",6,"High","Uncertain","LRP5-V667M",true,"pathogenic","Homozygous",1]
481	["pathogenic","0.0439673",4,"Low","Uncertain","TLR5-R392X",true,"pathogenic","Heterozygous",0]
482	["pathogenic","0.0439673",4,"Low","Uncertain","TLR5-R392X",true,"pathogenic","Homozygous",0]
483	["pathogenic","0.0480573",5,"Moderate","Likely","COL9A3-R103W",true,"pathogenic","Heterozygous",1]
484	["pathogenic","0.0480573",5,"Moderate","Likely","COL9A3-R103W",true,"pathogenic","Homozygous",1]
485	["pathogenic","0.048615",5,"Low","Likely","MBL2-R52C",true,"pathogenic","Carrier (Heterozygous)",-1]
486	["pathogenic","0.048615",5,"Low","Likely","MBL2-R52C",true,"pathogenic","Homozygous",1]
487	["pathogenic","0.0488858",5,"Low","Uncertain","TGFB1-R25P",true,"pathogenic","Heterozygous",0]
488	["pathogenic","0.0488858",5,"Low","Uncertain","TGFB1-R25P",true,"pathogenic","Homozygous",0]
489	["pathogenic","0.0494516",6,"Low","Well-established","HFE-C282Y",true,"pathogenic","Carrier (Heterozygous)",-1]
490	["pathogenic","0.0494516",6,"Low","Well-established","HFE-C282Y",true,"pathogenic","Homozygous",1]
491	["pathogenic","0.0521472",4,"Low","Likely","KRT5-G138E",true,"pathogenic","Heterozygous",-1]
492	["pathogenic","0.0521472",4,"Low","Likely","KRT5-G138E",true,"pathogenic","Homozygous",-1]
493	["pathogenic","0.0561443",4,"Low","Likely","RPGRIP1L-A229T",true,"pathogenic","Heterozygous",-1]
494	["pathogenic","0.0581893",3,"Low","Uncertain","POLG-Q1236H",true,"pathogenic","Heterozygous",0]
495	["pathogenic","0.0581893",3,"Low","Uncertain","POLG-Q1236H",true,"pathogenic","Homozygous",0]
496	["pathogenic","0.0613424",3,"High","Uncertain","RYR2-G1886S",true,"pathogenic","Carrier (Heterozygous)",-1]
497	["pathogenic","0.0613424",3,"High","Uncertain","RYR2-G1886S",true,"pathogenic","Homozygous",1]
498	["pathogenic","0.0613497",3,"Moderate","Uncertain","OPTN-M98K",true,"pathogenic","Heterozygous",-1]
499	["pathogenic","0.0632088",3,"Low","Uncertain","CLEC7A-Y238X",true,"pathogenic","Carrier (Heterozygous)",-1]
500	["pathogenic","0.0632088",3,"Low","Uncertain","CLEC7A-Y238X",true,"pathogenic","Homozygous",1]
501	["pathogenic","0.0646151",2,"Low","Likely","APOA5-S19W",true,"pathogenic","Heterozygous",-1]
502	["pathogenic","0.0646151",2,"Low","Likely","APOA5-S19W",true,"pathogenic","Homozygous",-1]
503	["pathogenic","0.0930643",3,"Low","Likely","AMPD1-Q12X",true,"pathogenic","Carrier (Heterozygous)",-1]
504	["pathogenic","0.0930643",3,"Low","Likely","AMPD1-Q12X",true,"pathogenic","Homozygous",1]
505	["pathogenic","0.103923",4,"Low","Likely","MBL2-G54D",true,"pathogenic","Carrier (Heterozygous)",-1]
506	["pathogenic","0.103923",4,"Low","Likely","MBL2-G54D",true,"pathogenic","Homozygous",1]
507	["pathogenic","0.109965",5,"Low","Uncertain","HFE-H63D",true,"pathogenic","Carrier (Heterozygous)",-1]
508	["pathogenic","0.109965",5,"Low","Uncertain","HFE-H63D",true,"pathogenic","Homozygous",1]
509	["pathogenic","0.110367",4,"Low","Uncertain","LRP5-A1330V",true,"pathogenic","Heterozygous",0]
510	["pathogenic","0.110367",4,"Low","Uncertain","LRP5-A1330V",true,"pathogenic","Homozygous",0]
511	["pathogenic","0.132664",2,"Low","Likely","FCGR2B-I232T",true,"pathogenic","Heterozygous",0]
512	["pathogenic","0.132664",2,"Low","Likely","FCGR2B-I232T",true,"pathogenic","Homozygous",0]
513	["pathogenic","0.135392",3,"High","Well-established","APOE-C130R",true,"pathogenic","Heterozygous",0]
514	["pathogenic","0.135392",3,"High","Well-established","APOE-C130R",true,"pathogenic","Homozygous",0]
515	["pathogenic","0.138889",3,"Low","Uncertain","TGIF1-P83Shift",true,"pathogenic","Heterozygous",0]
516	["pathogenic","0.138889",3,"Low","Uncertain","TGIF1-P83Shift",true,"pathogenic","Homozygous",0]
517	["pathogenic","0.152073",3,"Moderate","Likely","C3-R102G",true,"pathogenic","Heterozygous",0]
518	["pathogenic","0.152073",3,"Moderate","Likely","C3-R102G",true,"pathogenic","Homozygous",0]
519	["pathogenic","0.196877",4,"Low","Uncertain","ERCC6-R1213G",true,"pathogenic","Carrier (Heterozygous)",-1]
520	["pathogenic","0.196877",4,"Low","Uncertain","ERCC6-R1213G",true,"pathogenic","Homozygous",1]
521	["pathogenic","0.20147",3,"Low","Uncertain","DYX1C1-E417X",true,"pathogenic","Heterozygous",-1]
522	["pathogenic","0.20147",3,"Low","Uncertain","DYX1C1-E417X",true,"pathogenic","Homozygous",-1]
523	["pathogenic","0.214878",1,"Low","Likely","rs5186",true,"pathogenic","Heterozygous",-1]
524	["pathogenic","0.214878",1,"Low","Likely","rs5186",true,"pathogenic","Homozygous",-1]
525	["pathogenic","0.23656",4,"Low","Uncertain","BRCA2-N372H",true,"pathogenic","Carrier (Heterozygous)",-1]
526	["pathogenic","0.23656",4,"Low","Uncertain","BRCA2-N372H",true,"pathogenic","Homozygous",1]
527	["pathogenic","0.247537",2,"Low","Likely","PIGR-A580V",true,"pathogenic","Heterozygous",0]
528	["pathogenic","0.247537",2,"Low","Likely","PIGR-A580V",true,"pathogenic","Homozygous",0]
529	["pathogenic","0.273471",3,"Low","Uncertain","ELAC2-S217L",true,"pathogenic","Heterozygous",0]
530	["pathogenic","0.273471",3,"Low","Uncertain","ELAC2-S217L",true,"pathogenic","Homozygous",0]
531	["pathogenic","0.278026",4,"Low","Uncertain","RNASEL-R462Q",true,"pathogenic","Heterozygous",0]
532	["pathogenic","0.278026",4,"Low","Uncertain","RNASEL-R462Q",true,"pathogenic","Homozygous",0]
533	["pathogenic","0.308886",4,"Low","Uncertain","H6PD-R453Q",true,"pathogenic","Carrier (Heterozygous)",-1]
534	["pathogenic","0.308886",4,"Low","Uncertain","H6PD-R453Q",true,"pathogenic","Homozygous",1]
535	["pathogenic","0.324689",4,"Low","Likely","COL4A1-Q1334H",true,"pathogenic","Heterozygous",1]
536	["pathogenic","0.324689",4,"Low","Likely","COL4A1-Q1334H",true,"pathogenic","Homozygous",1]
537	["pathogenic","0.451199",4,"Low","Likely","MTRR-I49M",true,"pathogenic","Carrier (Heterozygous)",-1]
538	["pathogenic","0.451199",4,"Low","Likely","MTRR-I49M",true,"pathogenic","Homozygous",1]
539	["pathogenic","0.627743",4,"Low","Uncertain","TP53-P72R",true,"pathogenic","Heterozygous",-1]
540	["pathogenic","0.627743",4,"Low","Uncertain","TP53-P72R",true,"pathogenic","Homozygous",-1]
541	["pathogenic","0.863357",4,"Low","Uncertain","SP110-L425S",true,"pathogenic","Heterozygous",-1]
542	["pathogenic","0.863357",4,"Low","Uncertain","SP110-L425S",true,"pathogenic","Homozygous",-1]
543	["pathogenic","",1,"High","Uncertain","AARS2-G965R",true,"pathogenic","Carrier (Heterozygous)",-1]
544	["pathogenic","",1,"High","Uncertain","DCAF8-R317C",true,"pathogenic","Heterozygous",1]
545	["pathogenic","",1,"Low","Uncertain","ABCB6-R723Q",true,"pathogenic","Heterozygous",1]
546	["pathogenic","",1,"Low","Uncertain","DHTKD1-G729R",true,"pathogenic","Carrier (Heterozygous)",-1]
547	["pathogenic","",1,"Low","Uncertain","PLCD1-A574T",true,"pathogenic","Heterozygous",1]
548	["pathogenic","",1,"Moderate","Likely","TGDS-A100S",true,"pathogenic","Carrier (Heterozygous)",-1]
549	["pathogenic","",1,"Moderate","Uncertain","C7-R521S",true,"pathogenic","Carrier (Heterozygous)",-1]
550	["pathogenic","",1,"Moderate","Uncertain","CACNA1B-R1389H",true,"pathogenic","Heterozygous",1]
551	["pathogenic","",1,"Moderate","Uncertain","SCN11A-L1158P",true,"pathogenic","Heterozygous",1]
552	["pathogenic","",1,"Moderate","Uncertain","SERPINA6-L115H",true,"pathogenic","Carrier (Heterozygous)",-1]
553	["pathogenic","",1,"Moderate","Uncertain","SLC26A8-R87Q",true,"pathogenic","Heterozygous",1]
554	["pathogenic","",1,"Moderate","Well-established","BCHE-D98G",true,"pathogenic","Carrier (Heterozygous)",-1]
555	["pathogenic","",2,"High","Likely","FAM161A-R437X",true,"pathogenic","Carrier (Heterozygous)",-1]
556	["pathogenic","",2,"High","Uncertain","GDF6-D57H",true,"pathogenic","Carrier (Heterozygous)",-1]
557	["pathogenic","",2,"High","Uncertain","NPHS1-R256W",true,"pathogenic","Carrier (Heterozygous)",-1]
558	["pathogenic","",2,"High","Well-established","CCDC40-A83Shift",true,"pathogenic","Carrier (Heterozygous)",-1]
559	["pathogenic","",2,"High","Well-established","F11-F301L",true,"pathogenic","Carrier (Heterozygous)",-1]
560	["pathogenic","",2,"High","Well-established","MUTYH-G369D",true,"pathogenic","Carrier (Heterozygous)",-1]
561	["pathogenic","",2,"Low","Uncertain","AGBL1-R1028X",true,"pathogenic","Heterozygous",1]
562	["pathogenic","",2,"Moderate","Uncertain","CDKN2A-P11PAAGSSMEP",true,"pathogenic","Homozygous",1]
563	["pathogenic","",2,"Moderate","Uncertain","KCNV2-K3Shift",true,"pathogenic","Carrier (Heterozygous)",-1]
564	["pathogenic","",3,"High","Likely","ACE-R496X",true,"pathogenic","Carrier (Heterozygous)",-1]
565	["pathogenic","",3,"High","Likely","GBA-L483P",true,"pathogenic","Carrier (Heterozygous)",-1]
566	["pathogenic","",3,"High","Likely","PAH-A403V",true,"pathogenic","Carrier (Heterozygous)",-1]
567	["pathogenic","",3,"High","Uncertain","ALPL-E298K",true,"pathogenic","Carrier (Heterozygous)",-1]
568	["pathogenic","",3,"High","Uncertain","ATP7B-T991M",true,"pathogenic","Carrier (Heterozygous)",-1]
569	["pathogenic","",3,"High","Uncertain","CFTR-F1052V",true,"pathogenic","Carrier (Heterozygous)",-1]
570	["pathogenic","",3,"High","Uncertain","COL6A3-P3082R",true,"pathogenic","Carrier (Heterozygous)",-1]
571	["pathogenic","",3,"High","Uncertain","EMD-R157Q",true,"pathogenic","Homozygous",-1]
572	["pathogenic","",3,"High","Uncertain","FGB-R47X",true,"pathogenic","Carrier (Heterozygous)",-1]
573	["pathogenic","",3,"High","Uncertain","KCNH2-A913V",true,"pathogenic","Heterozygous",1]
574	["pathogenic","",3,"High","Uncertain","MYL2-N47K",true,"pathogenic","Heterozygous",1]
575	["pathogenic","",3,"High","Uncertain","VPS13B-N2968S",true,"pathogenic","Carrier (Heterozygous)",-1]
576	["pathogenic","",3,"High","Well-established","CFTR-F508Del",true,"pathogenic","Carrier (Heterozygous)",-1]
577	["pathogenic","",3,"High","Well-established","MYBPC3-R502W",true,"pathogenic","Heterozygous",1]
578	["pathogenic","",3,"High","Well-established","MYOT-S60C",true,"pathogenic","Heterozygous",1]
579	["pathogenic","",3,"High","Well-established","NCF1-Y26Shift",true,"pathogenic","Carrier (Heterozygous)",-1]
580	["pathogenic","",3,"Low","Well-established","HBD-A28S",true,"pathogenic","Carrier (Heterozygous)",-1]
581	["pathogenic","",3,"Moderate","Uncertain","ATP1A2-R383H",true,"pathogenic","Heterozygous",1]
582	["pathogenic","",3,"Moderate","Uncertain","COL2A1-T1439M",true,"pathogenic","Heterozygous",1]
583	["pathogenic","",3,"Moderate","Uncertain","NPC2-V30M",true,"pathogenic","Carrier (Heterozygous)",-1]
584	["pathogenic","",3,"Moderate","Uncertain","SCN9A-I720K",true,"pathogenic","Heterozygous",1]
585	["pathogenic","",3,"Moderate","Well-established","TYR-T373K",true,"pathogenic","Carrier (Heterozygous)",-1]
586	["pathogenic","",4,"High","Likely","LRP5-R1534X",true,"pathogenic","Carrier (Heterozygous)",-1]
587	["pathogenic","",4,"High","Likely","PPT1-T75P",true,"pathogenic","Carrier (Heterozygous)",-1]
588	["pathogenic","",4,"High","Uncertain","CEP290-D983Shift",true,"pathogenic","Carrier (Heterozygous)",-1]
589	["pathogenic","",4,"High","Uncertain","COL7A1-P2847Shift",true,"pathogenic","Carrier (Heterozygous)",-1]
590	["pathogenic","",4,"High","Uncertain","MYBPC3-E334K",true,"pathogenic","Heterozygous",1]
591	["pathogenic","",4,"High","Uncertain","SHH-V13Shift",true,"pathogenic","Heterozygous",1]
592	["pathogenic","",4,"High","Well-established","BRCA1-D1162Shift",true,"pathogenic","Heterozygous",1]
593	["pathogenic","",4,"High","Well-established","BRCA1-V340Shift",true,"pathogenic","Heterozygous",1]
594	["pathogenic","",4,"High","Well-established","BRCA2-F1866Shift",true,"pathogenic","Heterozygous",-1]
595	["pathogenic","",4,"High","Well-established","BRCA2-K3084Shift",true,"pathogenic","Heterozygous",1]
596	["pathogenic","",4,"High","Well-established","BRCA2-N1198Shift",true,"pathogenic","Heterozygous",-1]
597	["pathogenic","",4,"High","Well-established","BRCA2-S1982Shift",true,"pathogenic","Heterozygous",1]
598	["pathogenic","",4,"High","Well-established","CYP21A2-Q319X",true,"pathogenic","Carrier (Heterozygous)",-1]
599	["pathogenic","",4,"Moderate","Uncertain","EDNRB-Y293Shift",true,"pathogenic","Heterozygous",0]
600	["pathogenic","",4,"Moderate","Uncertain","STRC-Q1353X",true,"pathogenic","Heterozygous",1]
601	["pathogenic","",4,"Moderate","Uncertain","SYNE1-E6786Shift",true,"pathogenic","Carrier (Heterozygous)",-1]
602	["pathogenic","",5,"High","Uncertain","CLCNKB-W610X",true,"pathogenic","Carrier (Heterozygous)",-1]
603	["pathogenic","",5,"High","Uncertain","ITGB2-G273R",true,"pathogenic","Carrier (Heterozygous)",-1]
604	["pathogenic","",5,"High","Uncertain","LHX4-R84C",true,"pathogenic","Heterozygous",1]
605	["pathogenic","",5,"Moderate","Well-established","SLC22A12-W258X",true,"pathogenic","Carrier (Heterozygous)",-1]
606	["pathogenic","",6,"High","Uncertain","FANCI-R1285X",true,"pathogenic","Carrier (Heterozygous)",-1]
607	["pathogenic","",6,"High","Well-established","RDH12-R62X",true,"pathogenic","Carrier (Heterozygous)",-1]
608	["pathogenic","",6,"Moderate","Uncertain","SCN9A-I62V",true,"pathogenic","Heterozygous",1]
609	["pathogenic","9.2954e-05",4,"Moderate","Uncertain","DSP-L1489R",true,"pathogenic","Carrier (Heterozygous)",-1]
610	["pathogenic","9.2954e-05",5,"Moderate","Uncertain","SLC6A5-T425M",true,"pathogenic","Carrier (Heterozygous)",-1]
611	["pharmacogenetic","0.00362521",3,"High","Well-established","BCHE-G418V",true,"pharmacogenetic","Carrier (Heterozygous)",-1]
612	["pharmacogenetic","0.0044618",5,"Low","Uncertain","KCNE2-T8A",true,"pharmacogenetic","Heterozygous",1]
613	["pharmacogenetic","0.0109686",4,"Low","Uncertain","ADRB2-T164I",true,"pharmacogenetic","Heterozygous",-1]
614	["pharmacogenetic","0.015625",3,"Low","Uncertain","AQP1-A45V",true,"pharmacogenetic","Heterozygous",0]
615	["pharmacogenetic","0.0280774",3,"Low","Likely","TPMT-A154T",true,"pharmacogenetic","Carrier (Heterozygous)",-1]
616	["pharmacogenetic","0.0280774",3,"Low","Likely","TPMT-A154T",true,"pharmacogenetic","Homozygous",1]
617	["pharmacogenetic","0.0461825",4,"Low","Well-established","TPMT-Y240C",true,"pharmacogenetic","Heterozygous",0]
618	["pharmacogenetic","0.0461825",4,"Low","Well-established","TPMT-Y240C",true,"pharmacogenetic","Homozygous",0]
619	["pharmacogenetic","0.0609779",2,"Low","Well-established","ITPA-P32T",true,"pharmacogenetic","Carrier (Heterozygous)",-1]
620	["pharmacogenetic","0.0609779",2,"Low","Well-established","ITPA-P32T",true,"pharmacogenetic","Homozygous",1]
621	["pharmacogenetic","0.0778955",4,"High","Likely","DPYD-M166V",true,"pharmacogenetic","Heterozygous",-1]
622	["pharmacogenetic","0.0778955",4,"High","Likely","DPYD-M166V",true,"pharmacogenetic","Homozygous",-1]
623	["pharmacogenetic","0.0970982",3,"Moderate","Well-established","CYP2C9-R144C",true,"pharmacogenetic","Heterozygous",-1]
624	["pharmacogenetic","0.0970982",3,"Moderate","Well-established","CYP2C9-R144C",true,"pharmacogenetic","Homozygous",-1]
625	["pharmacogenetic","0.218907",4,"Low","Uncertain","ABCC6-R1268Q",true,"pharmacogenetic","Heterozygous",-1]
626	["pharmacogenetic","0.218907",4,"Low","Uncertain","ABCC6-R1268Q",true,"pharmacogenetic","Homozygous",-1]
627	["pharmacogenetic","0.351562",1,"Low","Uncertain","rs1544410",true,"pharmacogenetic","Heterozygous",-1]
628	["pharmacogenetic","0.351562",1,"Low","Uncertain","rs1544410",true,"pharmacogenetic","Homozygous",-1]
629	["pharmacogenetic","0.570312",2,"Low","Likely","PECAM1-L125V",true,"pharmacogenetic","Heterozygous",0]
630	["pharmacogenetic","0.570312",2,"Low","Likely","PECAM1-L125V",true,"pharmacogenetic","Homozygous",0]
631	["protective","0.00102268",4,"Low","Uncertain","PCSK9-R237W",true,"protective","Heterozygous",1]
632	["protective","0.00241681",5,"Low","Uncertain","TTR-T139M",true,"protective","Heterozygous",1]
633	["protective","0.0101389",3,"Moderate","Likely","PCSK9-R46L",true,"protective","Heterozygous",-1]
634	["protective","0.016174",3,"Low","Uncertain","MC4R-V103I",true,"protective","Heterozygous",-1]
635	["protective","0.016174",3,"Low","Uncertain","MC4R-V103I",true,"protective","Homozygous",-1]
636	["protective","0.0205429",4,"Low","Uncertain","BRCA2-T1915M",true,"protective","Heterozygous",-1]
637	["protective","0.0205429",5,"Low","Uncertain","TGFB1-T263I",true,"protective","Heterozygous",1]
638	["protective","0.0205429",5,"Low","Uncertain","TGFB1-T263I",true,"protective","Homozygous",1]
639	["protective","0.0351366",4,"Low","Uncertain","DTNBP1-P272S",true,"protective","Carrier (Heterozygous)",-1]
640	["protective","0.035843",2,"Low","Uncertain","LIG4-A3V",true,"protective","Heterozygous",1]
641	["protective","0.035843",2,"Low","Uncertain","LIG4-A3V",true,"protective","Homozygous",1]
642	["protective","0.046875",6,"Low","Uncertain","CFB-L9H",true,"protective","Heterozygous",-1]
643	["protective","0.046875",6,"Low","Uncertain","CFB-L9H",true,"protective","Homozygous",-1]
644	["protective","0.0474066",5,"Low","Likely","CASP10-V410I",true,"protective","Heterozygous",1]
645	["protective","0.0474066",5,"Low","Likely","CASP10-V410I",true,"protective","Homozygous",1]
646	["protective","0.047619",2,"Low","Well-established","CCR5-S185Shift",true,"protective","Carrier (Heterozygous)",-1]
647	["protective","0.047619",2,"Low","Well-established","CCR5-S185Shift",true,"protective","Homozygous",1]
648	["protective","0.0684142",4,"Low","Likely","ABCG5-R50C",true,"protective","Heterozygous",-1]
649	["protective","0.0684142",4,"Low","Likely","ABCG5-R50C",true,"protective","Homozygous",-1]
650	["protective","0.0844953",5,"Low","Uncertain","LPL-S474X",true,"protective","Heterozygous",-1]
651	["protective","0.0844953",5,"Low","Uncertain","LPL-S474X",true,"protective","Homozygous",-1]
652	["protective","0.102993",3,"Low","Likely","TOR1A-D216H",true,"protective","Heterozygous",-1]
653	["protective","0.102993",3,"Low","Likely","TOR1A-D216H",true,"protective","Homozygous",-1]
654	["protective","0.117188",4,"Moderate","Likely","CFB-R32Q",true,"protective","Heterozygous",1]
655	["protective","0.117188",4,"Moderate","Likely","CFB-R32Q",true,"protective","Homozygous",1]
656	["protective","0.210169",3,"Low","Likely","IL7R-T244I",true,"protective","Heterozygous",-1]
657	["protective","0.210169",3,"Low","Likely","IL7R-T244I",true,"protective","Homozygous",-1]
658	["protective","0.217234",4,"Low","Uncertain","MTR-D919G",true,"protective","Heterozygous",0]
659	["protective","0.217234",4,"Low","Uncertain","MTR-D919G",true,"protective","Homozygous",0]
660	["protective","0.232615",2,"Low","Uncertain","IRS2-G1057D",true,"protective","Heterozygous",-1]
661	["protective","0.232615",2,"Low","Uncertain","IRS2-G1057D",true,"protective","Homozygous",-1]
662	["protective","0.295687",4,"Low","Likely","NPC1-H215R",true,"protective","Heterozygous",0]
663	["protective","0.295687",4,"Low","Likely","NPC1-H215R",true,"protective","Homozygous",0]
664	["protective","0.339561",4,"Low","Well-established","PRNP-M129V",true,"protective","Heterozygous",0]
665	["protective","0.339561",4,"Low","Well-established","PRNP-M129V",true,"protective","Homozygous",0]
666	["protective","0.391616",3,"Low","Likely","CFH-V62I",true,"protective","Heterozygous",0]
667	["protective","0.391616",3,"Low","Likely","CFH-V62I",true,"protective","Homozygous",0]
668	["protective","0.490519",2,"Moderate","Well-established","FUT2-W154X",true,"protective","Carrier (Heterozygous)",-1]
669	["protective","0.490519",2,"Moderate","Well-established","FUT2-W154X",true,"protective","Homozygous",1]
670	["protective","0.738148",4,"Low","Likely","KCNJ11-K23E",true,"protective","Heterozygous",-1]
671	["protective","0.738148",4,"Low","Likely","KCNJ11-K23E",true,"protective","Homozygous",-1]
672	["protective","",5,"Low","Uncertain","PRNP-E219K",true,"protective","Heterozygous",0]